Alzheimer Papers
2023
Protocol for observing microtubules and microtubule ends in both fixed and live primary microglia cells
This paper presents a detailed protocol for studying microtubules in microglia cells, both in fixed and live states.
Unlocking Neural Function with 3D In Vitro Models: A Technical Review of Brain Organoids
A comprehensive review of 3D brain organoids and their applications in neurodevelopmental and neurodegenerative research.
A model eye for fluorescent characterization of retinal cultures and tissues
This study introduces a model for retinal cultures, advancing the characterization of retinal tissue.
Microglia reactivity entails microtubule remodeling from acentrosomal to centrosomal arrays
This research explores microtubule remodeling in reactive microglia and its implications for neuroinflammatory processes.
Retinal fingerprints of ALS in patients: Ganglion cell apoptosis and TDP-43/p62 misplacement
A novel study identifying retinal biomarkers in ALS patients, focusing on ganglion cell apoptosis.
2022
Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity
This study demonstrates the homeostatic plasticity of cortical neurons derived from human iPSCs.
Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons
The paper presents a novel BODIPY-based probe for imaging tau tangles, crucial in Alzheimer’s disease research.
Stem cell-based 3D brain organoids for mimicking and investigating Alzheimer's diseases
This review discusses how stem cell-derived 3D brain organoids can be used to study Alzheimer's disease.
2021
Editorial: Seeing Beyond the Eye: The Brain Connection
An editorial discussing the critical connection between eye health and brain function in neurodegenerative diseases.
Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease
This paper explores how a targeted antibody can reduce retinal degeneration in a mouse model of Alzheimer's disease.
Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs
This study presents new 2D and 3D brain models derived from FMRP-KO iPSCs for studying fragile X syndrome.
2020
Molecular Imaging of Tau Protein: New Insights and Future Directions
A paper discussing the advancements and future directions in molecular imaging techniques for tau protein in Alzheimer's.
Retinal and Brain Organoids: Bridging the Gap Between in vivo Physiology and in vitro Micro-Physiology for Alzheimer's Disease
This study highlights how retinal and brain organoids are used to model Alzheimer's disease, connecting in vivo and in vitro research.
iPS, organoids and 3D models as advanced tools for in vitro toxicology
A comprehensive overview of how induced pluripotent stem cells (iPS), organoids, and 3D models are transforming in vitro toxicology studies.
2019
Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer's Disease Patients
This study explores neuroinflammation, astrocyte activation, and protein aggregation as potential biomarkers for early Alzheimer's diagnosis.
Scattering assisted imaging
This paper introduces a novel scattering-assisted imaging technique that enhances resolution for biological specimens.
3D Bioprinted Human Cortical Neural Constructs Derived from Induced Pluripotent Stem Cells
This research focuses on creating 3D bioprinted human cortical neural constructs using iPSCs for neurodegenerative disease modeling.
WO2019186393 - Scattering-Assisted Super-Localization Microscopy Method and Relative Apparatus
This patent presents a method for super-localization microscopy, which significantly improves the resolution of biological imaging.
2018
Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer's disease in the 3xTg-AD mouse model
This paper investigates ocular biomarkers in Alzheimer's disease, specifically focusing on inflammation and protein aggregation in the retina.